Who is sponsoring NCT00018200?

NCT00018200 is sponsored by US Department of Veterans Affairs.

What condition does NCT00018200 study?

NCT00018200 studies Back Pain, Sciatica.

What drugs are being tested in NCT00018200?

Interventions: Desipramine, Fluoxetine, Benztropine.

What is the status of NCT00018200?

NCT00018200 is currently COMPLETED.

Last reviewed 2012-06-04 · How we verify

Efficacy of Antidepressants in Chronic Back Pain

NCT00018200 Phase 2 COMPLETED

The purpose of this study is to determine whether different types of antidepressant medicines relieve back pain that has lasted at least six months on a daily basis. Study participants will be assigned to treatment with either a antidepressant acting on the serotonin system in the brain (fluoxetine), one acting on the noradrenaline system (desipramine, or to a control medication not expected to relieve pain (benztropine). Each participant will be seen at least nine times during their 12 weeks on medication. This is a phase 2/3, outpatient study.

Details

Lead sponsor	US Department of Veterans Affairs
Phase	Phase 2
Status	COMPLETED
Enrolment	130
Start date	1999-04
Completion	2004-03

Conditions

Back Pain
Sciatica

Interventions

Desipramine
Fluoxetine
Benztropine

Primary outcomes

Descriptor Differential Scale Pain Intensity — 12 weeks post baseline

Countries

United States