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Phase II Study of Multimodality Therapy in Mantle Cell Lymphoma
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining chemotherapy with peripheral stem cell or bone marrow transplantation may allow the doctor to give higher doses of chemotherapy drugs and kill more cancer cells. Biological therapies use different ways to stimulate the immune system and stop cancer cells from growing. PURPOSE: Phase II trial to study the effectiveness of combination chemotherapy followed by bone marrow or peripheral stem cell transplantation and/or biological therapy in treating patients who have stage III, stage IV, or recurrent mantle cell lymphoma.
Details
| Lead sponsor | Northwestern University |
|---|---|
| Phase | Phase 2 |
| Status | COMPLETED |
| Start date | 1999-10 |
| Completion | 2006-08 |
Conditions
- Lymphoma
Interventions
- aldesleukin
- filgrastim
- recombinant interferon alfa
- busulfan
- cyclophosphamide
- cytarabine
- doxorubicin hydrochloride
- leucovorin calcium
- methotrexate
- prednisone
Countries
United States