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A Phase III Study of Doxorubicin-Cyclophosphamide Therapy Followed by Paclitaxel or Docetaxel Given Weekly or Every 3 Weeks in Patients With Axillary Node-Positive Breast Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. It is not yet known which regimen of chemotherapy is more effective for breast cancer. PURPOSE: Randomized phase III trial to compare the effectiveness of two different regimens of combination chemotherapy in treating women who have stage II or stage IIIA breast cancer that has spread to the lymph nodes.
Details
| Lead sponsor | Eastern Cooperative Oncology Group |
|---|---|
| Phase | Phase 3 |
| Status | COMPLETED |
| Start date | 1999-11-16 |
| Completion | 2016-11 |
Conditions
- Breast Cancer
Interventions
- cyclophosphamide
- docetaxel
- doxorubicin hydrochloride
- paclitaxel
- tamoxifen citrate
- radiation therapy
Countries
United States