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A UKLG Randomised Trial of Initial Chemotherapy for Advanced Stage Hodgkins Disease
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. It is not yet known which chemotherapy regimen is more effective for advanced Hodgkin's disease. PURPOSE: Randomized phase III trial to compare different combination chemotherapy regimens in treating patients with advanced Hodgkin's disease.
Details
| Lead sponsor | Medical Research Council |
|---|---|
| Phase | Phase 3 |
| Status | COMPLETED |
| Enrolment | 800 |
| Start date | 1998-06 |
| Completion | 2005-11 |
Conditions
- Lymphoma
Interventions
- bleomycin sulfate
- ABVD regimen
- chlorambucil
- dacarbazine
- doxorubicin hydrochloride
- etoposide
- prednisolone
- procarbazine hydrochloride
- vinblastine sulfate
- vincristine sulfate
Countries
United Kingdom