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MMT 95 Study For Rhabdomyosarcoma and Other Malignant Soft Tissue Tumors of Childhood
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one chemotherapy drug with surgery and/or radiation therapy may kill more tumor cells. PURPOSE: This randomized phase III trial is studying surgery followed by different regimens of combination chemotherapy given together with radiation therapy and/or additional surgery to compare how well they work in treating patients with soft tissue sarcoma.
Details
| Lead sponsor | Societe Internationale d'Oncologie Pediatrique |
|---|---|
| Phase | Phase 3 |
| Status | COMPLETED |
| Enrolment | 400 |
| Start date | 1995-01 |
| Completion | 2009-12 |
Conditions
- Childhood Malignant Fibrous Histiocytoma of Bone
- Sarcoma
Interventions
- dactinomycin
- carboplatin
- cyclophosphamide
- epirubicin hydrochloride
- etoposide
- ifosfamide
- vincristine sulfate
- adjuvant therapy
- conventional surgery
- neoadjuvant therapy
Countries
United Kingdom