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NCT00002872
A PROSPECTIVE RANDOMIZED TRIAL OF BLEOMYCIN VS. DOXYCYCLINE VS. TALC FOR THE INTRAPLEURAL TREATMENT OF MALIGNANT PLEURAL EFFUSIONS
Phase 3 trial testing bleomycin sulfate in Metastatic Cancer in 480 participants. Completed.
1 February 2003
Quick facts
| Lead sponsor | Eastern Cooperative Oncology Group |
|---|---|
| Phase | Phase 3 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Primary purpose | supportive care |
| Enrollment | 480 |
| Start date | 10 January 1997 |
| Primary completion | 1 February 2003 |
Drugs / interventions tested
- bleomycin sulfate — full drug profile →
- doxycycline (doxycycline) — full drug profile →
- talc (TALC) — full drug profile →
Conditions studied
- Metastatic Cancer — all drugs for Metastatic Cancer →
Sponsor
Eastern Cooperative Oncology Group
Who can join
Adults 18 to 120, any sex, with Metastatic Cancer. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
RATIONALE: Some drugs such as bleomycin or doxycycline, or other compounds like talc, may help to control fluid in the chest caused by cancer. It is not yet known if bleomycin, doxycycline, or talc is more effective in treating patients with malignant pleural effusions. PURPOSE: Randomized phase III trial to compare the effectiveness of bleomycin, doxycycline, or talc in treating patients with malignant pleural effusions.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT00002872
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Currently open trials in the same condition.
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Other Eastern Cooperative Oncology Group trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT00002872 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Eastern Cooperative Oncology Group
- Last refreshed: 21 June 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT00002872.
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