AUTOLOGOUS STEM CELL TRANSPLANTATION FOR ACUTE MYELOID LEUKEMIA IN SECOND REMISSION: A PHASE II STUDY

NCT00002768 Phase 2 COMPLETED

RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining chemotherapy with peripheral stem cell transplantation may allow the doctor to give higher doses of chemotherapy drugs and kill more cancer cells. PURPOSE: Phase II trial to study the effectiveness of peripheral stem cell transplantation following chemotherapy in treating patients with acute myeloid leukemia in second remission.

Details

Lead sponsor	Alliance for Clinical Trials in Oncology
Phase	Phase 2
Status	COMPLETED
Enrolment	51
Start date	1996-06
Completion	2009-03

Conditions

• Leukemia

Interventions

• filgrastim
• busulfan
• cytarabine
• etoposide
• methotrexate
• peripheral blood stem cell transplantation

Primary outcomes

• Disease free survival — 2 years

Countries

United States