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NCT00001606
Genetic Analysis of Human Hereditary Hearing Impairment
trial in Partial Hearing Loss in 404 participants. Terminated before completion.
Quick facts
| Lead sponsor | National Institute on Deafness and Other Communication Disorders (NIDCD) |
|---|---|
| Status | Terminated |
| Study type | OBSERVATIONAL |
| Enrollment | 404 |
| Start date | 8 September 1997 |
| Estimated completion | 7 April 2015 |
| Sites | 1 location across United States |
Conditions studied
- Partial Hearing Loss — all drugs for Partial Hearing Loss →
Sponsor
National Institute on Deafness and Other Communication Disorders (NIDCD)
Who can join
Eligibility, any sex, with Partial Hearing Loss. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This studied is designed to discover the genes that cause hearing impairment. More precisely, this study aims to map and clone genes that are important for the development and maintenance of the anatomy and physiology related to hearing (auditory system). The study will begin by finding large families who have members with hearing impairment. Once families are found, members with and without hearing impairment will be evaluated by an audiologist and a clinician (doctor). An audiologist, is a person trained in evaluating, habilitating, and rehabilitating people with disorders of hearing function. The clinician's responsibility is to examine the patients and check for other signs and symptoms related to hearing. Finding the gene for hearing impairment requires: 1. \<TAB\>DNA samples of hearing impaired family members, taken from standard blood samples. 2. \<TAB\>DNA samples of members of the family without hearing impairment, taken from standard blood samples. 3. \<TAB\>Results of hearing tests conducted by the audiologist for all participants. Once all members of the family are evaluated researchers can create a pedigree. A pedigree is like a family tree that charts members of a family with a genetic disorder, like hearing impairment. Pedigrees are used to determine the mode of inheritance of the gene responsible for a particular condition. Finally, researcher intend on using all the information gathered as well as methods for genetic analysis to map out the location of the gene. Patients participating in this study will not directly benefit from its research, but scientific understanding achieved may help researchers better understand the auditory system and someday prevent deafness.\<TAB\>...
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT00001606
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT00001606 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by National Institute on Deafness and Other Communication Disorders (NIDCD)
- Last refreshed: 17 December 2019
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT00001606.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing