The Role of Hormones in Postpartum Mood Disorders

NCT00001481 PHASE2 COMPLETED Results posted

The present protocol is designed to create a "scaled-down" hormonal milieu of pregnancy and the puerperium in order to determine whether it is the abrupt withdrawal of gonadal steroids or the prolonged exposure to gonadal steroids that is associated with mood symptoms.

Details

Lead sponsor	National Institute of Mental Health (NIMH)
Phase	PHASE2
Status	COMPLETED
Enrolment	74
Start date	Fri Apr 26 1996 00:00:00 GMT+0000 (Coordinated Universal Time)
Completion	Fri Oct 25 2024 00:00:00 GMT+0000 (Coordinated Universal Time)

Conditions

• Postpartum Depression

Interventions

• Estradiol
• Placebo
• Progesterone
• leuprolide acetate

Countries

United States