RAD-1: A Phase I/II Antiretroviral Management Algorithm for Pediatric Subjects of Four-Drug Combination Therapies Based on Prior Antiretroviral Experience

NCT00000902 Phase 1 COMPLETED

The purpose of this study is to determine the value of changing anti-HIV medications in children with progressive HIV disease who have received previous treatment. Plasma viral load (the level of HIV in the blood) is probably most effectively reduced by giving patients anti-HIV drugs which affect the virus at various stages of development. Changing the medications may enhance the results of treatment.

Details

Lead sponsor	National Institute of Allergy and Infectious Diseases (NIAID)
Phase	Phase 1
Status	COMPLETED
Enrolment	217
Completion	2002-04

Conditions

• HIV Infections

Interventions

• Ritonavir
• Nelfinavir mesylate
• Nevirapine
• Lamivudine
• Stavudine
• Zidovudine
• Zalcitabine
• Didanosine

Countries

United States, Puerto Rico