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Ganciclovir-Cidofovir CMV Retinitis Trial (GCCRT)
To compare cidofovir with a commonly used treatment regimen, ganciclovir given by mouth (oral) and through an eye device (intraocular) , in order to determine the safety and effectiveness of cidofovir in preventing vision loss in patients who have AIDS complicated by CMV (cytomegalovirus) retinitis. Cidofovir needs to be compared to ganciclovir to determine the best way to treat CMV retinitis.
Details
| Lead sponsor | National Institute of Allergy and Infectious Diseases (NIAID) |
|---|---|
| Phase | Phase 4 |
| Status | COMPLETED |
| Enrolment | 300 |
Conditions
- Cytomegalovirus Retinitis
- HIV Infections
Interventions
- Cidofovir
- Probenecid
- Ganciclovir
Countries
United States