Vasopressin V2 receptor — Drug Target

All drugs that target Vasopressin V2 receptor — marketed and clinical-stage. Includes 6 drug classes acting on this target.

Drug classes

Vasopressin V2 Receptor Antagonist [EPC] · mozavaptan · Vasopressin Receptor Antagonist · Vasopressin V2 receptor antagonist (vaptан) · Vasopressin V2 receptor antagonist · Vasopressin V2-receptor antagonist (vaptans)

Marketed (3)

• Samsca · Otsuka · Vasopressin V2 Receptor Antagonist [EPC] · Metabolic
  Samsca works by blocking the action of vasopressin, a hormone that regulates water levels in the body.
• Physulime · Otsuka Pharmaceutical Co., Ltd. · mozavaptan · Hematology
• Vaprisol In 5% Dextrose In Plastic Container · Cumberland · Vasopressin Receptor Antagonist · Cardiovascular

Phase 3 pipeline (4)

• OPC-41061 · Otsuka Pharmaceutical Co., Ltd. · Vasopressin V2 receptor antagonist (vaptан) · Cardiovascular / Nephrology
  OPC-41061 is a vasopressin V2 receptor antagonist (vaptан) that blocks water reabsorption in the kidney collecting duct, promoting aquaresis and increasing serum sodium levels.
• Tolvaptan or Samsca · Cardiovascular Clinical Sciences Inc · Vasopressin V2 receptor antagonist · Cardiovascular
  Tolvaptan is a selective, competitive antagonist of the vasopressin V2 receptor.
• Tolvaptan Oral Tablet · Otsuka Pharmaceutical Co., Ltd. · Vasopressin V2-receptor antagonist (vaptans) · Nephrology / Endocrinology
  Tolvaptan is a selective vasopressin V2-receptor antagonist that blocks water reabsorption in the kidney's collecting duct, promoting aquaresis (water excretion) without significant electrolyte loss.
• OPC-41061 （Tolvaptan) · Otsuka Pharmaceutical Co., Ltd. · Vasopressin V2 receptor antagonist · Cardiovascular
  Tolvaptan is a selective, competitive antagonist of the vasopressin V2 receptor.