Topoisomerase I and thymidylate synthase — Drug Target

All drugs that target Topoisomerase I and thymidylate synthase — marketed and clinical-stage. Includes 1 drug classes acting on this target.

Drug classes

Topoisomerase I inhibitor and thymidylate synthase inhibitor

Phase 3 pipeline (1)

• capecitabine-irinotecan · Dutch Colorectal Cancer Group · Topoisomerase I inhibitor and thymidylate synthase inhibitor · Oncology
  Capecitabine-irinotecan combines a prodrug of fluorouracil with a topoisomerase I inhibitor to target rapidly dividing cancer cells.