TLR7 — Drug Target

All drugs that target TLR7 — marketed and clinical-stage. Includes 2 drug classes acting on this target.

Drug classes

Toll-like receptor 7 (TLR7) agonist · TLR7 agonist

Marketed (2)

• Imiquimod 5% Topical Cream · University of Michigan · Toll-like receptor 7 (TLR7) agonist · Dermatology/Oncology
  Imiquimod is a toll-like receptor 7 (TLR7) agonist that activates innate immune responses to enhance local antiviral and antitumor immunity.
• Aldara Cream 5% · Hordinsky, Maria K., MD · Toll-like receptor 7 (TLR7) agonist · Dermatology/Oncology
  Imiquimod is a toll-like receptor 7 (TLR7) agonist that activates innate immune responses to treat skin lesions.

Phase 3 pipeline (2)

• Aldara 5% Topical Cream · University Medical Centre Maribor · Toll-like receptor 7 (TLR7) agonist · Dermatology/Oncology
  Imiquimod is a toll-like receptor 7 (TLR7) agonist that activates innate immune responses to treat skin lesions.
• IV Tulisokibart · Merck Sharp & Dohme LLC · TLR7 agonist · Oncology
  Tulisokibart is a TLR7 agonist that activates innate immune responses to enhance anti-tumor immunity.

Phase 2 pipeline (1)

• EL219 · Elion Therapeutics, Inc. · TLR7 agonist · Oncology
  EL219 is an immunostimulatory agent designed to activate innate immune responses against cancer.