Tissue factor — Drug Target

All drugs that target Tissue factor — marketed and clinical-stage. Includes 3 drug classes acting on this target.

Drug classes

Antibody-drug conjugate · Antibody-Drug Conjugate (ADC) · Tissue factor inhibitor

Marketed (2)

• Tivdak · SEAGEN · Antibody-drug conjugate · Oncology
  Tisotumab vedotin is a tissue factor (TF)-directed antibody drug conjugate that targets and disrupts microtubule networks in cancer cells.
• Tisotumab Vedotin · SEAGEN · Antibody-Drug Conjugate (ADC) · Oncology

Phase 2 pipeline (1)

• AMG 853 · Amgen · Tissue factor inhibitor · Cardiovascular
  AMG 853 is a recombinant, humanized monoclonal antibody that targets and neutralizes tissue factor.