Prostacyclin receptor — Drug Target

All drugs that target Prostacyclin receptor — marketed and clinical-stage. Includes 5 drug classes acting on this target.

Drug classes

Prostacycline Vasodilator [EPC] · Prostacyclin Receptor Agonist [EPC] · prostacyclin analogue · Prostacyclin analogue · beraprost

Marketed (3)

• Remodulin · United Therap · Prostacycline Vasodilator [EPC] · Cardiovascular
  Remodulin works by activating the prostacyclin receptor, which causes blood vessels to relax and widen.
• Uptravi · AstraZeneca · Prostacyclin Receptor Agonist [EPC] · Metabolic
  Uptravi works by activating the prostacyclin receptor, which helps to relax blood vessels and improve blood flow.
• Flolan · AstraZeneca · Prostacycline Vasodilator [EPC] · Cardiovascular
  Flolan works by binding to the prostacyclin receptor, causing blood vessels to relax and dilate.

Phase 3 pipeline (4)

• iloprost (5 µg) · Actelion · prostacyclin analogue · Cardiovascular
  Iloprost is a prostacyclin analogue that acts as a vasodilator and inhibits platelet aggregation.
• iloprost nebuliser solution · Shanghai Jiao Tong University School of Medicine · Prostacyclin analogue · Cardiovascular
  Iloprost is a prostacyclin analogue that acts as a vasodilator and inhibits platelet aggregation.
• Ventavis (Iloprost, BAYQ6256) · Bayer · Prostacyclin analogue · Cardiovascular
  Ventavis is a prostacyclin analogue that acts as a vasodilator to improve exercise capacity in patients with pulmonary arterial hypertension.
• Treprostinil Injectable Product · University of Arizona · Prostacyclin analogue · Pulmonology
  Treprostinil is a prostacyclin analogue that acts as a vasodilator and inhibits platelet aggregation.