Phosphodiesterase — Drug Target

All drugs that target Phosphodiesterase — marketed and clinical-stage. Includes 2 drug classes acting on this target.

Drug classes

Methylxanthine derivative; phosphodiesterase inhibitor · Phosphodiesterase inhibitor

Marketed (1)

• Pentoxifylline sustained-release tablets · Beijing Tiantan Hospital · Methylxanthine derivative; phosphodiesterase inhibitor · Cardiovascular
  Pentoxifylline improves blood flow and reduces inflammation by inhibiting phosphodiesterase enzymes and modulating cytokine production.

Phase 3 pipeline (1)

• pentoxyphylline (PTX) · National Taiwan University Hospital · Phosphodiesterase inhibitor · Cardiovascular
  Pentoxyphylline (PTX) is a methylxanthine derivative that acts as a phosphodiesterase inhibitor, increasing cyclic AMP levels and improving blood flow.

Phase 2 pipeline (2)

• EHT 0202 etazolate · Exonhit · Phosphodiesterase inhibitor · Neurology
  Etazolate is a phosphodiesterase inhibitor.
• Defibrotide Injection · IRCCS San Raffaele · Phosphodiesterase inhibitor · Oncology
  Phosphodiesterase inhibitor