P2X7 — Drug Target

All drugs that target P2X7 — marketed and clinical-stage. Includes 1 drug classes acting on this target.

Drug classes

P2X7 receptor antagonist

Phase 3 pipeline (4)

• OPC-6535 Tablets (drug) · Otsuka Pharmaceutical Development & Commercialization, Inc. · P2X7 receptor antagonist · Immunology
  OPC-6535 is a selective antagonist of the P2X7 receptor, an ATP-gated ion channel involved in inflammatory and immune responses.
• OPC-6535 · Otsuka Pharmaceutical Co., Ltd. · P2X7 receptor antagonist · Neurology / Pain
  OPC-6535 is a selective antagonist of the P2X7 receptor, which modulates purinergic signaling involved in inflammatory and immune responses.
• GW685698 · GlaxoSmithKline · P2X7 receptor antagonist · Immunology
  GW685698 is a selective antagonist of the P2X7 receptor, an ATP-gated ion channel involved in inflammatory and immune responses.
• GW406381 · GlaxoSmithKline · P2X7 receptor antagonist · Immunology / Neurology
  GW406381 is a selective antagonist of the P2X7 receptor, an ATP-gated ion channel involved in inflammatory and immune responses.

Phase 2 pipeline (1)

• JTE-451 Tablets · Akros Pharma Inc. · P2X7 receptor antagonist · Immunology
  JTE-451 is a selective antagonist of the P2X7 receptor, which modulates immune cell activation and inflammatory responses.