NPC1L1 and HMG-CoA reductase — Drug Target

All drugs that target NPC1L1 and HMG-CoA reductase — marketed and clinical-stage. Includes 1 drug classes acting on this target.

Drug classes

Cholesterol absorption inhibitor and statin

Phase 3 pipeline (1)

• ezetimibe with simvastatin · Organon and Co · Cholesterol absorption inhibitor and statin · Cardiovascular
  Ezetimibe inhibits the absorption of cholesterol in the small intestine, while simvastatin is a statin that inhibits HMG-CoA reductase, a key enzyme in cholesterol synthesis.