fibrin — Drug Target

All drugs that target fibrin — marketed and clinical-stage. Includes 2 drug classes acting on this target.

Drug classes

Fibrinolytic enzyme · Thrombolytic

Marketed (2)

• Tnkase · Roche · Immunology
  Tenecteplase binds to fibrin and converts plasminogen to plasmin, enhancing fibrin-specific plasmin generation.
• Natto extract (Nattokinase) · Changhua Christian Hospital · Fibrinolytic enzyme · Cardiovascular
  Nattokinase is a serine protease enzyme that directly degrades fibrin clots and enhances fibrinolysis to promote thrombus dissolution.

Phase 3 pipeline (1)

• CureXcell · Macrocure Ltd. · Thrombolytic · Cardiovascular
  CureXcell is a recombinant human thrombolytic enzyme.