Erythropoietin receptor — Drug Target

All drugs that target Erythropoietin receptor — marketed and clinical-stage. Includes 8 drug classes acting on this target.

Drug classes

Erythropoiesis-stimulating agent (ESA) · Erythropoiesis-stimulating Agent · Erythropoiesis-stimulating Agent [EPC] · erythropoiesis-stimulating agent · Erythropoiesis-stimulating agent · erythropoiesis-stimulating protein · Erythropoiesis-stimulating protein · Erythropoietin receptor agonist

Marketed (14)

• Epogen · Amgen · Erythropoiesis-stimulating agent (ESA) · Hematology
  Epoetin alfa stimulates erythropoiesis by the same mechanism as endogenous erythropoietin.
• Epogen · Amgen · Erythropoiesis-stimulating Agent · Metabolic
  Epogen works by binding to the erythropoietin receptor, triggering a cascade of signals that stimulate the production of red blood cells.
• Aranesp · Amgen · Erythropoiesis-stimulating Agent [EPC] · Hematology
  Aranesp works by binding to the erythropoietin receptor, mimicking the action of natural erythropoietin to stimulate red blood cell production.
• (F) RH-V14 · National Taiwan University Hospital · erythropoiesis-stimulating agent · Hematology
  RH-V14 is a recombinant human erythropoietin used to stimulate erythropoiesis.
• Neorecormon · Roche Registration Limited · Oncology
  Neorecormon works by binding to the erythropoietin receptor, mimicking the action of natural erythropoietin to stimulate red blood cell production.
• epoetin · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) · Erythropoiesis-stimulating agent (ESA) · Infectious Disease
  Epogen stimulates erythropoiesis by the same mechanism as endogenous erythropoietin.
• Silapo · Hospira UK Limited · Hematology
• Neorecormon · Centre Hospitalier Universitaire, Amiens · Oncology
• Mircera · Hoffman-La Roche · Metabolic
  Mircera activates erythropoietin receptors, increasing red cell production in response to hypoxia.
• Aranesp · University of Washington · Hematology
• Mircera · Samsung Medical Center · Hematology
• Eporatio · Hematology
• Erythropoietin · Nanjing First Hospital, Nanjing Medical University · Hematology
• Darbepoetin · NICHD Neonatal Research Network · Hematology

Phase 3 pipeline (11)

• pegol-Sihematide · Jiangsu Hansoh Pharmaceutical Co., Ltd. · Erythropoiesis-stimulating agent · Hematology
  Pegol-sihematide is a long-acting erythropoiesis-stimulating agent that promotes red blood cell production.
• epoetin alfa + packed RBC transfusion · Janssen Research & Development, LLC · erythropoiesis-stimulating protein · Oncology
  Epoetin alfa stimulates erythropoiesis by binding to the erythropoietin receptor, promoting the production of red blood cells.
• Placebo of Darbepoetin alfa · Bayer · Erythropoiesis-stimulating protein · Oncology, Hematology
  Darbepoetin alfa is an erythropoiesis-stimulating protein that mimics the action of erythropoietin to stimulate red blood cell production.
• r-HuEPO · Sunnybrook Health Sciences Centre · erythropoiesis-stimulating agent · Oncology, Nephrology
  r-HuEPO is a recombinant form of human erythropoietin that stimulates red blood cell production.
• epoetin alfa or beta · Hoffmann-La Roche · erythropoiesis-stimulating agent · Oncology
  Epoetin alfa and beta stimulate erythropoiesis by binding to the erythropoietin receptor.
• stable erythropoietin therapy · American Regent, Inc. · erythropoiesis-stimulating agent · Hematology
  Stable erythropoietin therapy works by stimulating the production of red blood cells.
• darbepoetin alfa SF · Amgen · erythropoiesis-stimulating protein · Oncology
  Darbepoetin alfa SF stimulates erythropoiesis by binding to the erythropoietin receptor.
• NESP · Genexine, Inc. · erythropoiesis-stimulating agent · Nephrology
  NESP is a recombinant human erythropoietin analog that stimulates erythropoiesis.
• Open-label rusfertide · Protagonist Therapeutics, Inc. · Erythropoietin receptor agonist · Nephrology
  Rusfertide is a human erythropoietin receptor agonist.
• rhEPO · GlaxoSmithKline · erythropoiesis-stimulating agent · Oncology
  rhEPO stimulates erythropoiesis by binding to the erythropoietin receptor.
• US-licensed epoetin alfa · Sandoz · erythropoiesis-stimulating agent · Oncology, Nephrology
  Epoetin alfa stimulates erythropoiesis by binding to the erythropoietin receptor.

Phase 2 pipeline (3)

• C.E.R.A. · Hoffmann-La Roche · Erythropoiesis-stimulating agent · Oncology
  C.E.R.A. is a continuous erythropoietin receptor activator.
• Erythropoietin alpha · Mathew S. Maurer · erythropoiesis-stimulating agent · Oncology
  Erythropoietin alpha stimulates erythropoiesis by binding to the erythropoietin receptor.
• Epoetin biosimilar · Hospira, now a wholly owned subsidiary of Pfizer · Erythropoiesis-stimulating agent · Oncology
  Stimulates erythropoiesis by binding to the erythropoietin receptor

Phase 1 pipeline (1)

• A hydrogel containing erythropoietin · Remedor Biomed Ltd · Erythropoiesis-stimulating agent · Oncology
  Stimulates erythropoiesis by binding to and activating the erythropoietin receptor