CysLT1 receptor — Drug Target

All drugs that target CysLT1 receptor — marketed and clinical-stage. Includes 3 drug classes acting on this target.

Drug classes

Leukotriene receptor antagonist · Cysteinyl leukotriene receptor antagonist (LTRA) · Cysteinyl leukotriene receptor antagonist

Marketed (5)

• Montelukast placebo granüle · Kecioren Education and Training Hospital · Leukotriene receptor antagonist · Respiratory / Immunology
  Montelukast is a leukotriene receptor antagonist that blocks cysteinyl leukotriene receptors to reduce airway inflammation and bronchoconstriction.
• montelukast (Singulair) · University of Bologna · Cysteinyl leukotriene receptor antagonist (LTRA) · Respiratory / Immunology
  Montelukast blocks cysteinyl leukotriene receptors (CysLT1) on airway and immune cells, preventing leukotriene-mediated inflammation and bronchoconstriction.
• Montelukast (High FeNO group) · Hull University Teaching Hospitals NHS Trust · Leukotriene receptor antagonist · Respiratory
  Montelukast is a selective leukotriene receptor antagonist that blocks the action of cysteinyl leukotrienes on the CysLT1 receptor, reducing inflammation and bronchoconstriction.
• montelukast (MON) · GlaxoSmithKline · Cysteinyl leukotriene receptor antagonist (LTRA) · Respiratory / Immunology
  Montelukast blocks cysteinyl leukotriene receptors (CysLT1) on airway and immune cells, preventing leukotriene-mediated inflammation and bronchoconstriction.
• Montelukast (drug) · Firestone Institute for Respiratory Health · Cysteinyl leukotriene receptor antagonist (LTRA) · Respiratory / Immunology
  Montelukast blocks cysteinyl leukotriene receptors (CysLT1) on airway and immune cells, preventing leukotriene-mediated inflammation and bronchoconstriction.

Phase 3 pipeline (4)

• Pranlukast hydrate · SamA Pharmaceutical Co., Ltd · Leukotriene receptor antagonist · Respiratory
  Pranlukast hydrate is a leukotriene receptor antagonist that inhibits the action of leukotrienes, which are involved in the inflammatory process.
• Montelukast Oral Granules (OG) · Organon and Co · Leukotriene receptor antagonist · Respiratory / Immunology
  Montelukast blocks cysteinyl leukotriene receptors (CysLT1) on airway and inflammatory cells, preventing leukotriene-mediated bronchoconstriction and inflammation.
• BRL29060A · GlaxoSmithKline · Leukotriene receptor antagonist · Respiratory/Immunology
  BRL29060A is a leukotriene receptor antagonist that blocks cysteinyl leukotriene receptors to reduce inflammatory responses.
• Comparator: pranlukast · Organon and Co · Cysteinyl leukotriene receptor antagonist · Respiratory / Immunology
  Pranlukast is a cysteinyl leukotriene receptor antagonist that blocks the inflammatory effects of leukotrienes in the airways.