CXCR4 — Drug Target

All drugs that target CXCR4 — marketed and clinical-stage. Includes 1 drug classes acting on this target.

Drug classes

CXCR4 antagonist

Marketed (1)

• Fixed Dose Plerixafor · Genzyme, a Sanofi Company · CXCR4 antagonist · Oncology
  Plerixafor is a CXCR4 antagonist that mobilizes hematopoietic stem cells from the bone marrow into peripheral blood for collection and transplantation.

Phase 3 pipeline (2)

• Motixafortide+G-CSF · Guangzhou Gloria Biosciences Co., Ltd. · CXCR4 antagonist · Oncology
  Motixafortide is a CXCR4 antagonist that mobilizes hematopoietic stem cells from bone marrow into peripheral blood, used in combination with G-CSF (granulocyte-colony stimulating factor) to enhance stem cell mobilization for transplantation.
• Generic = Plerixafor · Genzyme, a Sanofi Company · CXCR4 antagonist · Oncology
  Plerixafor is a CXCR4 chemokine receptor antagonist that mobilizes hematopoietic stem cells from the bone marrow into peripheral blood.