Complement Factor D — Drug Target

All drugs that target Complement Factor D — marketed and clinical-stage. Includes 2 drug classes acting on this target.

Drug classes

Complement Factor D Inhibitor · Complement Factor D inhibitor

Marketed (1)

• DANICOPAN · Complement Factor D Inhibitor · Other
  Danicopan is a selective inhibitor of complement Factor D, preventing the cleavage of Factor B and the formation of the C3 convertase in the alternative complement pathway.

Phase 3 pipeline (1)

• CYB704 · Sandoz · Complement Factor D inhibitor · Immunology
  CYB704 is a selective inhibitor of complement factor D that reduces complement cascade activation and downstream inflammatory responses.