CGRP receptor — Drug Target

All drugs that target CGRP receptor — marketed and clinical-stage. Includes 2 drug classes acting on this target.

Drug classes

CGRP receptor antagonist · monoclonal antibody

Marketed (1)

• ZAVEGEPANT
  Zavegepant blocks CGRP receptors to prevent migraine.

Phase 3 pipeline (2)

• Placebo to telcagepant tablets · Merck Sharp & Dohme LLC · CGRP receptor antagonist · Neurology
  Telcagepant is a calcitonin gene-related peptide receptor antagonist.
• Placebo to Telcagepant · Merck Sharp & Dohme LLC · CGRP receptor antagonist · Neurology
  Telcagepant is a calcitonin gene-related peptide receptor antagonist.

Phase 2 pipeline (5)

• Erenumab Auto-Injector · Clinique des Céphalées de Montréal · monoclonal antibody · Neurology
  Erenumab is a human monoclonal antibody that targets the calcitonin gene-related peptide (CGRP) receptor.
• Any treatment for cluster headache · Samsung Medical Center · CGRP receptor antagonist · Neurology
  This drug targets the calcitonin gene-related peptide (CGRP) receptor to prevent cluster headache attacks.
• AMG 334 Dose 1 · Amgen · CGRP receptor antagonist · Neurology
  AMG 334 is a fully human monoclonal antibody that targets and inhibits the activity of the calcitonin gene-related peptide (CGRP) receptor.
• BHV-2100 · Biohaven Therapeutics Ltd. · CGRP receptor antagonist · Neurology
  BHV-2100 is a calcitonin gene-related peptide receptor antagonist.
• BHV-7000 · Biohaven Therapeutics Ltd. · CGRP receptor antagonist · Neurology
  BHV-7000 is a calcitonin gene-related peptide receptor antagonist.