Catechol O-methyltransferase — Drug Target

All drugs that target Catechol O-methyltransferase — marketed and clinical-stage. Includes 3 drug classes acting on this target.

Drug classes

Catechol-O-Methyltransferase Inhibitor [EPC] · broxyquinoline · chiniofon

Marketed (3)

• Ongentys · Neurocrine Biosciences · Catechol-O-Methyltransferase Inhibitor [EPC] · Metabolic
  Ongentys works by blocking the enzyme that breaks down dopamine, allowing more dopamine to be available in the brain.
• Dibromoxin · broxyquinoline · Other
• Comtan · Orion Pharma · Catechol-O-Methyltransferase Inhibitor [EPC] · Metabolic
  Comtan works by blocking the enzyme catechol-O-methyltransferase, which breaks down dopamine in the brain.

Phase 2 pipeline (2)

• CHINIOFON · chiniofon · Other
  CHINIOFON is thought to work by interacting with a specific biological target, but the exact mechanism is not well understood.
• Cospanon · Dermatology
  FLOPROPIONE works by inhibiting the enzyme Catechol O-methyltransferase, which plays a role in the regulation of bile flow.