ATR — Drug Target

All drugs that target ATR — marketed and clinical-stage. Includes 2 drug classes acting on this target.

Drug classes

ATR kinase inhibitor · ATR inhibitor

Phase 1 pipeline (3)

• Administration of AZD6738 · AstraZeneca · ATR kinase inhibitor · Oncology
  AZD6738 is a selective inhibitor of ataxia telangiectasia and Rad3-related (ATR) kinase, which plays a critical role in the DNA damage response pathway.
• Administration of ceralasertib monotherapy · AstraZeneca · ATR inhibitor · Oncology
  Ceralasertib is an ATP-competitive inhibitor of the serine/threonine kinase ATR, which is involved in DNA damage response pathways.
• AZD5363when combined with weekly paclitaxel. · AstraZeneca · ATR kinase inhibitor · Oncology
  ATR kinase inhibitor