5-HT4 receptor — Drug Target

All drugs that target 5-HT4 receptor — marketed and clinical-stage. Includes 2 drug classes acting on this target.

Drug classes

5-HT4 receptor agonist · 5-HT4 receptor partial agonist

Phase 3 pipeline (4)

• OPN-375 · Optinose US Inc. · 5-HT4 receptor agonist · Gastroenterology
  OPN-375 is a selective serotonin 5-HT4 receptor agonist that enhances gastric motility and accelerates gastric emptying.
• Mosapride Citrate Tablets · Xiyuan Hospital of China Academy of Chinese Medical Sciences · 5-HT4 receptor agonist · Gastroenterology
  Mosapride citrate is a 5-HT4 receptor agonist that enhances gastric motility and accelerates gastric emptying.
• S-268019-b · Shionogi · 5-HT4 receptor partial agonist · Gastroenterology
  S-268019-b is a selective serotonin 5-HT4 receptor partial agonist that enhances gastric motility and accelerates gastric emptying.
• DA-5219 · Dong-A ST Co., Ltd. · 5-HT4 receptor partial agonist · Gastroenterology
  DA-5219 is a selective serotonin 5-HT4 receptor partial agonist that enhances gastric motility and accelerates gastric emptying.