US Patent

US9994576 — Substituted pyrazolo[3,4-d]pyrimidines as kinase inhibitors

Method of Use · Assigned to Principia Biopharma Inc · Expires 2033-09-06 · 7y remaining

Vulnerability score 75/100 Vulnerable — likely target for IPR or design-around

What this patent protects

This patent protects compounds that are tyrosine kinase inhibitors, specifically BTK inhibitors, and their pharmaceutical compositions for treating diseases such as cancer and arthritis.

USPTO Abstract

The present disclosure provides compounds of Formula (II) as disclosed herein, and/or pharmaceutically acceptable salts thereof that are tyrosine kinase inhibitors, in particular BTK inhibitors, and are potentially useful for the treatment of diseases treatable by inhibition of tyrosine kinases such as cancer, inflammatory diseases such as arthritis, and the like. Also provided are pharmaceutical compositions containing such compounds and/or pharmaceutically acceptable salts thereof and processes for preparing such compounds and pharmaceutically acceptable salts thereof.

Drugs covered by this patent

FDA Patent Use Codes

When a patent is method-of-use, FDA lists it once per applicable indication ("U-code"). Each U-code carves out a specific therapeutic use that generic filers must either license or design around.

CodeDescriptionDrug
U-4268 Wayrilz

Patent Metadata

Patent number
US9994576
Jurisdiction
US
Classification
Method of Use
Expires
2033-09-06
Drug substance claim
Yes
Drug product claim
Yes
Assignee
Principia Biopharma Inc
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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