US Patent

US9926559 — Compositions and methods for modulation of SMN2 splicing in a subject

Method of Use · Assigned to Biogen MA Inc · Expires 2034-01-09 · 8y remaining

Vulnerability score 62/100 Moderate — design-around opportunities exist

What this patent protects

This patent protects methods for modulating SMN2 splicing in a subject using compounds and compositions, including for the treatment of spinal muscular atrophy.

USPTO Abstract

Disclosed herein are compounds, compositions and methods for modulating splicing of SMN2 mRNA in a subject. Also provided are uses of disclosed compounds and compositions in the manufacture of a medicament for treatment of diseases and disorders, including spinal muscular atrophy.

Drugs covered by this patent

nusinersen-sodium (NUSINERSEN SODIUM)

FDA Patent Use Codes

When a patent is method-of-use, FDA lists it once per applicable indication ("U-code"). Each U-code carves out a specific therapeutic use that generic filers must either license or design around.

Code	Description	Drug
`U-1943`	—	nusinersen-sodium

Patent Metadata

Patent number: US9926559
Jurisdiction: US
Classification: Method of Use
Expires: 2034-01-09
Drug substance claim: No
Drug product claim: No
Assignee: Biogen MA Inc
Source: FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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