US Patent

US9751887 — Imidazo[1,2-b]pyridazine derivatives as kinase inhibitors

Method of Use · Assigned to Daiichi Sankyo Co Ltd · Expires 2033-06-03 · 7y remaining

Vulnerability score 75/100 Vulnerable — likely target for IPR or design-around

What this patent protects

This patent protects a compound or its pharmacologically acceptable salt that inhibits ROS1 and NTRK kinase enzymes, useful in treating a tumor.

USPTO Abstract

The present invention is intended to provide a compound or a pharmacologically acceptable salt thereof which is useful in the treatment of a tumor through its ROS1 kinase enzyme activity inhibitory effect and NTRK kinase enzyme inhibitory effect. The present invention provides a compound having an imidazo[1,2-b]pyridazine structure represented by the general formula (I) or a pharmacologically acceptable salt thereof, and a pharmaceutical composition comprising the compound. In the formula, R 1 , G, T, Y 1 , Y 2 , Y 3 , and Y 4 are as defined herein.

Drugs covered by this patent

FDA Patent Use Codes

When a patent is method-of-use, FDA lists it once per applicable indication ("U-code"). Each U-code carves out a specific therapeutic use that generic filers must either license or design around.

CodeDescriptionDrug
U-4207 taletrectinib-adipate

Patent Metadata

Patent number
US9751887
Jurisdiction
US
Classification
Method of Use
Expires
2033-06-03
Drug substance claim
Yes
Drug product claim
Yes
Assignee
Daiichi Sankyo Co Ltd
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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