US9693978 — Solvent system for enhancing the solubility of pharmaceutical agents
Formulation · Assigned to Banner Life Sciences LLC · Expires 2026-03-03 · 0y expired
What this patent protects
This patent protects a solvent system for enhancing the solubility of pharmaceutical agents, specifically a liquid or semi-solid composition containing a salt of an active agent and a de-ionizing agent.
USPTO Abstract
Liquid and semi-solid pharmaceutical compositions, which can be administered in liquid form or can be used for preparing capsules, are described herein. The composition comprises the salt of one ore more active agents, polyethylene glycol, 0.2-1.0 mole equivalents of a de-ionizing agent per mole of active agent, and water. The pH of the composition is adjusted within the range of 2.5-7.5. The de-ionizing agent causes partial de-ionization (neutralization) of the salt of the active agent resulting in enhanced bioavailability of salts of weakly acidic, basic or amphoteric active agents as well as lesser amounts of polyethylene glycol (PEG) esters.
Drugs covered by this patent
Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.
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