US9669019 — Sublingual apomorphine
Method of Use · Assigned to Sunovion Pharmaceuticals Inc · Expires 2030-06-11 · 4y remaining
What this patent protects
This patent protects sublingual formulations of apomorphine in unit dosage form, specifically mucoadhesive films containing a pH neutralizing agent and apomorphine particles.
USPTO Abstract
Disclosed are sublingual formulations of apomorphine in unit dosage form formulated for sublingual administration, where the unit dosage form is a mucoadhesive film containing a pH neutralizing agent and apomorphine particles containing an acid addition salt of apomorphine, and where the mucoadhesive film is formed by the steps of: (i) combining a film-forming mucoadhesive polymer, apomorphine particles comprising an acid addition salt of apomorphine, and a solvent to form a mixture; and (ii) pouring the mixture onto a surface and evaporating some of the solvent to form a first film comprising the apomorphine particles, where the steps further include contacting or impregnating the first film or mixture with a pH neutralizing agent to produce the mucoadhesive film containing the apomorphine particles and the pH neutralizing agent.
Drugs covered by this patent
FDA Patent Use Codes
When a patent is method-of-use, FDA lists it once per applicable indication ("U-code"). Each U-code carves out a specific therapeutic use that generic filers must either license or design around.
| Code | Description | Drug |
|---|---|---|
U-2825 |
— | apomorphine-hydrochloride |
U-2825 |
— | apomorphine-hydrochloride |
U-2825 |
— | apomorphine-hydrochloride |
U-2825 |
— | apomorphine-hydrochloride |
U-2825 |
— | apomorphine-hydrochloride |
Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.
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