US Patent

US9549923 — Benzoic acid, benzoic acid derivatives and heteroaryl carboxylic acid conjugates of hydrocodone, prodrugs, methods of making and uses thereof

Composition of Matter · Assigned to KemPharm Inc · Expires 2030-07-01 · 4y remaining

Vulnerability score 10/100 Ironclad — strong claim type, well-established, deep family

What this patent protects

This patent protects novel prodrugs of hydrocodone, including benzoates and heteroaryl carboxylic acids, that have a decreased potential for abuse.

USPTO Abstract

The presently described technology provides compositions comprising aryl carboxylic acids chemically conjugated to hydrocodone (morphinan-6-one, 4,5-alpha-epoxy-3-methoxy-17-methyl) to form novel prodrugs/compositions of hydrocodone, including benzoates and heteroaryl carboxylic acids, which have a decreased potential for abuse of hydrocodone. The present technology also provides methods of treating patients, pharmaceutical kits and methods of synthesizing conjugates of the present technology.

Drugs covered by this patent

Patent Metadata

Patent number
US9549923
Jurisdiction
US
Classification
Composition of Matter
Expires
2030-07-01
Drug substance claim
Yes
Drug product claim
Yes
Assignee
KemPharm Inc
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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