US9486451 — Abuse resistant pharmaceutical compositions
Method of Use · Assigned to Recro Gainesville LLC · Expires 2034-09-12 · 8y remaining
What this patent protects
This patent protects an oral pharmaceutical composition designed to prevent abuse of a susceptible active ingredient, such as hydrocodone bitartrate.
USPTO Abstract
The present invention relates to a composition comprising pharmaceutical active ingredients which are susceptible to, or have potential for, abuse. The invention provides an oral pharmaceutical composition comprising a first population of beads and a second population of beads. The first bead population comprises a pharmaceutically active ingredient susceptible to, or having the potential for, abuse. The second bead population comprises a gelling agent and a coating substantially surrounding the gelling agent, but containing no pharmaceutically active ingredient. The first bead population and the second bead population are physically separable, but visually indistinguishable to the naked eye. Upon ingress of water into the second population of beads, the gelling agent is caused to swell forming a viscous mass inhibiting or preventing the extraction of the active ingredient.
Drugs covered by this patent
FDA Patent Use Codes
When a patent is method-of-use, FDA lists it once per applicable indication ("U-code"). Each U-code carves out a specific therapeutic use that generic filers must either license or design around.
| Code | Description | Drug |
|---|---|---|
U-55 |
— | hydrocodone-bitartrate |
U-55 |
— | hydrocodone-bitartrate |
U-55 |
— | hydrocodone-bitartrate |
U-55 |
— | hydrocodone-bitartrate |
U-55 |
— | hydrocodone-bitartrate |
U-55 |
— | hydrocodone-bitartrate |
Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.
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