US9399774 — Modulation of transthyretin expression
Method of Use · Assigned to Ionis Pharmaceuticals Inc · Expires 2031-04-29 · 5y remaining
What this patent protects
This patent protects methods, compounds, and compositions that reduce expression of transthyretin mRNA and protein in an animal.
USPTO Abstract
Provided herein are methods, compounds, and compositions for reducing expression of transthyretin mRNA and protein in an animal. Such methods, compounds, and compositions are useful to treat, prevent, delay, or ameliorate transthyretin amyloidosis, or a symptom thereof.
Drugs covered by this patent
FDA Patent Use Codes
When a patent is method-of-use, FDA lists it once per applicable indication ("U-code"). Each U-code carves out a specific therapeutic use that generic filers must either license or design around.
| Code | Description | Drug |
|---|---|---|
U-2430 |
— | inotersen-sodium |
Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.
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