US Patent

US9308195 — Non-aqueous taxane formulations and methods of using the same

Formulation · Assigned to Teikoku Pharma USA Inc · Expires 2033-09-30 · 7y remaining

Vulnerability score 42/100 Strong — defensible against typical IPR challenges

What this patent protects

This patent protects non-aqueous, ethanol-free formulations of taxanes, including docetaxel, and methods of using these formulations.

USPTO Abstract

Non-aqueous, ethanol-free taxane formulations are provided. Formulations of embodiments of the invention include a taxane, an oil, a non-ionic surfactant, a non-aqueous solvent, and an organic acid component, wherein the organic acid component is soluble in the non-aqueous solvent and the amount by weight of non-ionic surfactant is equal to or greater than the amount by weight of non-aqueous solvent. Also provided are methods of using the formulations, as well as kits that include the formulations. Non-aqueous, ethanol-free docetaxel formulations are provided. Formulations of embodiments of the invention include docetaxel, an oil, a non-ionic surfactant, a non-aqueous solvent, and an organic acid which is soluble in the non-aqueous solvent and is substantially free of any conjugate base. Also provided are methods of using the formulations, as well as kits that include the formulations.

Drugs covered by this patent

Patent Metadata

Patent number
US9308195
Jurisdiction
US
Classification
Formulation
Expires
2033-09-30
Drug substance claim
No
Drug product claim
Yes
Assignee
Teikoku Pharma USA Inc
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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