US Patent

US9254341 — Methods of manufacture of pteroyl-amino acid-fluorescent dyes

Composition of Matter · Assigned to On Target Laboratories Inc · Expires 2033-10-04 · 7y remaining

Vulnerability score 12/100 Ironclad — strong claim type, well-established, deep family

What this patent protects

This patent discloses a process for preparing a compound, specifically pteroyl-amino acid-fluorescent dyes, including PAFOLACIANINE SODIUM.

USPTO Abstract

The present invention discloses a process for preparing a compound having the formula Including Reacting a compound of the formula 1: with a compound of the formula: in the presence of a polar solvent and trifluoroacetic acid to provide a compound of the formula: or a racemic mixture thereof; and further reacting the compound of the formula: or a racemic mixture thereof; with sodium hydroxide and a compound of the formula: wherein R 1 and R 2 are as defined above.

Drugs covered by this patent

Patent Metadata

Patent number
US9254341
Jurisdiction
US
Classification
Composition of Matter
Expires
2033-10-04
Drug substance claim
Yes
Drug product claim
Yes
Assignee
On Target Laboratories Inc
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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