US Patent

US8993600 — Modulators of ATP-binding cassette transporters

Formulation · Assigned to Vertex Pharmaceuticals Inc · Expires 2030-12-11 · 5y remaining

Vulnerability score 39/100 Strong — defensible against typical IPR challenges

What this patent protects

This patent protects compounds that modulate ATP-Binding Cassette transporters, including those used to treat diseases such as cystic fibrosis.

USPTO Abstract

Compounds of the present invention, and pharmaceutically acceptable compositions thereof, are useful as modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator (“CFTR”). The present invention also relates to methods of treating ABC transporter mediated diseases using compounds of the present invention.

Drugs covered by this patent

Patent Metadata

Patent number
US8993600
Jurisdiction
US
Classification
Formulation
Expires
2030-12-11
Drug substance claim
No
Drug product claim
Yes
Assignee
Vertex Pharmaceuticals Inc
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

Track this patent

Get a daily-checked alert when vulnerability score, expiry, classification, or assignee changes. Email, Slack, or Teams delivery. Pro: 50 watches, Free: 3.