US Patent

US8987463 — Methods of synthesizing factor Xa inhibitors

Formulation · Assigned to Millennium Pharmaceuticals Inc · Expires 2030-12-28 · 5y remaining

Vulnerability score 48/100 Strong — defensible against typical IPR challenges

What this patent protects

This patent protects methods for synthesizing betrixaban, a compound also known as Bevyxxa, and compositions comprising substantially pure betrixaban.

USPTO Abstract

Described herein are novel methods of preparing a compound of Formula II or a pharmaceutically acceptable salt thereof. In some embodiments, the method is for preparing betrixaban or a pharmaceutically acceptable salt thereof. Also described are compositions comprising substantially pure betrixaban free base or salt thereof.

Drugs covered by this patent

Patent Metadata

Patent number
US8987463
Jurisdiction
US
Classification
Formulation
Expires
2030-12-28
Drug substance claim
No
Drug product claim
Yes
Assignee
Millennium Pharmaceuticals Inc
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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