US8883842 — Use of HDAC inhibitors for the treatment of myeloma
Method of Use · Assigned to Novartis AG · Expires 2028-06-13 · 2y remaining
What this patent protects
This patent protects the use of a specific type of HDAC inhibitor, such as panobinostat lactate, for treating myeloma, including multiple myeloma that is resistant to conventional chemotherapy.
USPTO Abstract
The present invention relates to the use of an HDAC inhibitor, especially an HDAC inhibitor of formula (I) wherein the radicals and symbols have the meanings as defined in the specification, for the preparation of a medicament for the treatment of myeloma, in particular, multiple myeloma, especially myeloma which is resistant to conventional chemotherapy; to a combination comprising an HDAC inhibitor and a compound effecting apoptosis of myeloma cells, preferably bortezomib, for simultaneous, separate or sequential use; to methods of treating myeloma; and to a pharmaceutical composition comprising said combination.
Drugs covered by this patent
FDA Patent Use Codes
When a patent is method-of-use, FDA lists it once per applicable indication ("U-code"). Each U-code carves out a specific therapeutic use that generic filers must either license or design around.
| Code | Description | Drug |
|---|---|---|
U-1669 |
— | panobinostat-lactate |
U-1669 |
— | panobinostat-lactate |
U-1669 |
— | panobinostat-lactate |
Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.
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