US Patent

US8877247 — Abuse-deterrent multi-layer pharmaceutical composition comprising an opioid antagonist and an opioid agonist

Formulation · Assigned to Alpharma Pharmaceuticals LLC · Expires 2027-06-19 · 1y remaining

Vulnerability score 60/100 Moderate — design-around opportunities exist

What this patent protects

This patent protects a multi-layer pharmaceutical composition that includes an opioid antagonist and an opioid agonist, such as morphine sulfate, with a seal coat separating the two.

USPTO Abstract

Provided herein is a pharmaceutical composition comprising an antagonist, an agonist, a seal coat, and a sequestering polymer, wherein the antagonist, agonist, seal coat and at least one sequestering polymer are all components of a single unit, and wherein the seal coat forms a layer physically separating the antagonist from the agonist from one another. Methods for manufacturing such a pharmaceutical composition are also provided.

Drugs covered by this patent

Patent Metadata

Patent number
US8877247
Jurisdiction
US
Classification
Formulation
Expires
2027-06-19
Drug substance claim
No
Drug product claim
Yes
Assignee
Alpharma Pharmaceuticals LLC
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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