US Patent

US8778305 — PSMA-binding agents and uses thereof

Method of Use · Assigned to Johns Hopkins University · Expires 2030-09-21 · 4y remaining

Vulnerability score 81/100 Vulnerable — likely target for IPR or design-around

What this patent protects

This patent protects compounds that bind to prostate-specific membrane antigen (PSMA) and can be used for imaging, such as with single photon emission computed tomography (SPECT) or positron emission tomography (PET).

USPTO Abstract

Prostate-specific membrane antigen (PSMA) binding compounds having radioisotope substituents are described, as well as chemical precursors thereof. Compounds include pyridine containing compounds, compounds having phenylhydrazine structures, and acylated lysine compounds. The compounds allow ready incorporation of radionuclides for single photon emission computed tomography (SPECT) and positron emission tomography (PET) for imaging, for example, prostate cancer cells and angiogenesis.

Drugs covered by this patent

FDA Patent Use Codes

When a patent is method-of-use, FDA lists it once per applicable indication ("U-code"). Each U-code carves out a specific therapeutic use that generic filers must either license or design around.

CodeDescriptionDrug
U-3317 —
U-3130 —

Patent Metadata

Patent number
US8778305
Jurisdiction
US
Classification
Method of Use
Expires
2030-09-21
Drug substance claim
Yes
Drug product claim
Yes
Assignee
Johns Hopkins University
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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