US Patent

US8653058 — Compositions comprising deoxycholic acid and salts thereof suitable for use in treating fat deposits

Formulation · Assigned to Kythera Biopharmaceuticals LLC · Expires 2030-03-02 · 4y remaining

Vulnerability score 48/100 Strong — defensible against typical IPR challenges

What this patent protects

This patent protects an aqueous pharmaceutical composition containing a specific concentration of deoxycholic acid salt, stabilized at a pH range of 8.1 to 8.5.

USPTO Abstract

The present application is directed to an aqueous pharmaceutical composition comprising from about 0.4% w/v to less than about 2% w/v of a salt of deoxycholic acid, wherein the composition is maintained at a pH from about 8.1 to about 8.5 such that the composition is stabilized against precipitation. Also disclosed herein, are methods for stabilizing an aqueous pharmaceutical composition comprising from about 0.4% w/v to less than about 2% w/v of a salt of deoxycholic acid against precipitation, said method comprising maintaining pH of the solution from about 8.1 to about 8.5.

Drugs covered by this patent

Patent Metadata

Patent number
US8653058
Jurisdiction
US
Classification
Formulation
Expires
2030-03-02
Drug substance claim
No
Drug product claim
Yes
Assignee
Kythera Biopharmaceuticals LLC
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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