US Patent

US8642075 — Lipid-based compositions of antiinfectives for treating pulmonary infections and methods of use thereof

Formulation · Assigned to Insmed Inc · Expires 2026-12-05 · 1y remaining

Vulnerability score 60/100 Moderate — design-around opportunities exist

What this patent protects

This patent protects a system for treating or preventing pulmonary infections using a pharmaceutical formulation of an antiinfective, such as amikacin sulfate, in a lipid-based composition.

USPTO Abstract

A system for treating or providing prophylaxis against a pulmonary infection is disclosed comprising: a) a pharmaceutical formulation comprising a mixture of free antiinfective and antiinfective encapsulated in a lipid-based composition, and b) an inhalation delivery device. A method for providing prophylaxis against a pulmonary infection in a patient and a method of reducing the loss of antiinfective encapsulated in a lipid-based composition upon nebulization comprising administering an aerosolized pharmaceutical formulation comprising a mixture of free antiinfective and antiinfective encapsulated in a lipid-based composition is also disclosed.

Drugs covered by this patent

Patent Metadata

Patent number
US8642075
Jurisdiction
US
Classification
Formulation
Expires
2026-12-05
Drug substance claim
No
Drug product claim
Yes
Assignee
Insmed Inc
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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