US Patent

US8637553 — Fluoro substituted omega-carboxyaryl diphenyl urea for the treatment and prevention of diseases and conditions

Composition of Matter · Assigned to Bayer Healthcare LLC · Expires 2031-02-16 · 5y remaining

Vulnerability score 15/100 Ironclad — strong claim type, well-established, deep family

What this patent protects

This patent protects a compound of Formula (I) and its salts, prodrugs, and metabolites for treating diseases mediated by raf, VEGFR, PDGFR, p38, and flt-3.

USPTO Abstract

A compound of Formula (I): salts thereof, prodrugs thereof, metabolites thereof, pharmaceutical compositions containing such a compound, and use of such compound and compositions to treat diseases mediated by raf, VEGFR, PDGFR, p38 and flt-3.

Drugs covered by this patent

chembl-chembl1946170 (REGORAFENIB)

Patent Metadata

Patent number: US8637553
Jurisdiction: US
Classification: Composition of Matter
Expires: 2031-02-16
Drug substance claim: Yes
Drug product claim: Yes
Assignee: Bayer Healthcare LLC
Source: FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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