US Patent

US8481573 — Modulators of sphingosine phosphate receptors

Method of Use · Assigned to Scripps Research Institute · Expires 2033-03-24 · 7y remaining

Vulnerability score 62/100 Moderate — design-around opportunities exist

What this patent protects

This patent protects compounds that activate a specific receptor and are useful in treating conditions such as multiple sclerosis, transplant rejection, and adult respiratory syndrome.

USPTO Abstract

Compounds of the following generic structure are provided: Such compounds activate a sphingosine-I-phosphate receptor of the subtype 1 (S1P1), and have utility in the treatment of malconditions mediated by S1P1 activation. More specifically, such compounds are beneficial in the treatment of, for example, multiple sclerosis, transplant rejection and/or adult respiratory syndrome.

Drugs covered by this patent

FDA Patent Use Codes

When a patent is method-of-use, FDA lists it once per applicable indication ("U-code"). Each U-code carves out a specific therapeutic use that generic filers must either license or design around.

CodeDescriptionDrug
U-2774 ozanimod-hydrochloride
U-2774 ozanimod-hydrochloride
U-2774 ozanimod-hydrochloride

Patent Metadata

Patent number
US8481573
Jurisdiction
US
Classification
Method of Use
Expires
2033-03-24
Drug substance claim
Yes
Drug product claim
Yes
Assignee
Scripps Research Institute
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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