US Patent

US8450344 — Beta- and gamma-amino-isoquinoline amide compounds and substituted benzamide compounds

Method of Use · Assigned to Aerie Pharmaceuticals Inc · Expires 2026-07-11 · 0y remaining

Vulnerability score 80/100 Vulnerable — likely target for IPR or design-around

What this patent protects

This patent protects beta and gamma-amino isoquinoline amide compounds and substituted benzamide compounds useful as therapeutic agents for treating various diseases and conditions.

USPTO Abstract

Disclosed are beta and gamma-amino isoquinoline amide compounds and substituted benzamide compounds. In particular, the invention provides compounds that affect the function of kinases in a cell and that are useful as therapeutic agents or with therapeutic agents. The compounds of the invention are useful in the treatment of a variety of diseases and conditions including eye diseases such as glaucoma, cardiovascular diseases, and diseases characterized by abnormal growth, such as cancers. The invention further provides compositions containing the beta or gamma-amino isoquinoline amide compounds or substituted benzamide compounds.

Drugs covered by this patent

FDA Patent Use Codes

When a patent is method-of-use, FDA lists it once per applicable indication ("U-code"). Each U-code carves out a specific therapeutic use that generic filers must either license or design around.

CodeDescriptionDrug
U-1524
U-1524 Xalatan

Patent Metadata

Patent number
US8450344
Jurisdiction
US
Classification
Method of Use
Expires
2026-07-11
Drug substance claim
Yes
Drug product claim
Yes
Assignee
Aerie Pharmaceuticals Inc
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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