US Patent

US8357394 — Compositions and methods for improved efficacy of penicillin-type antibiotics

Formulation · Assigned to Shionogi Inc · Expires 2026-12-08 · 1y remaining

Vulnerability score 65/100 Moderate — design-around opportunities exist

What this patent protects

This patent protects once-a-day penicillin-type antibiotic products that maintain effective levels in the serum for at least 5 hours within a 24-hour dosing interval.

USPTO Abstract

Disclosed are once-a-day penicillin-type antibiotic products comprising at least one modified release dosage form comprising penicillin-type antibiotics and pharmaceutically acceptable carriers, which compositions provide T>MIC 90 in the serum for at least 5 hours (preferably for at least five consecutive hours), within a 24-hour dosing interval, for a given bacterial pathogen's MIC 90 , while providing a total dosage of the penicillin-type antibiotic for a 24-hour dosing interval.

Drugs covered by this patent

Patent Metadata

Patent number
US8357394
Jurisdiction
US
Classification
Formulation
Expires
2026-12-08
Drug substance claim
No
Drug product claim
Yes
Assignee
Shionogi Inc
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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