US8277780 — Stable liquid desoximethasone compositions with reduced oxidized impurity
Method of Use · Assigned to Taro Pharmaceuticals North America Inc · Expires 2028-09-01 · 2y remaining
What this patent protects
This patent protects a stable liquid formulation of the drug desoximetasone, specifically a liquid composition with certain percentages of desoximetasone, isopropyl myristate, and a C2-C4 alcohol.
USPTO Abstract
The present invention relates to a stable liquid formulation comprising desoximetasone, isopropyl myristate, a C2-C4 alcohol and a stabilizing agent. Specifically, the present invention provides a liquid formulation comprising: a) about 0.01 wt % to about 2.5 wt % desoximetasone; b) about 10 wt % to about 70 wt % isopropyl myristate; c) about 20 wt % to about 70 wt % C2-C4 alcohol; and d) a stabilizing agent selected from the group consisting of an oleaginous vehicle and a propellant, wherein the stabilizing agent is in an amount sufficient to reduce the formation of less than about 1 wt % 17-carboxy-9α-fluoro-11β-hydroxy-16a-methyl-androsta-1,4-diene-3-one under an accelerated storage condition.
Drugs covered by this patent
- Topicort (DESOXIMETASONE) · Taro
FDA Patent Use Codes
When a patent is method-of-use, FDA lists it once per applicable indication ("U-code"). Each U-code carves out a specific therapeutic use that generic filers must either license or design around.
| Code | Description | Drug |
|---|---|---|
U-1408 |
— | Topicort |
Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.
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